Transfection

News Transfection

• Photoactivable bioluminescent probe

  A group of scientists led by Bengang Xing, at Nanyang Technological University, Singapore, in collaboration with Zhen Cheng and colleagues at Stanford University Medical Centre, California, have developed a photoactivable bioluminescent probe for imaging luciferase activity in live cells. Firefl more

• Xantos Biomedicine and QIAGEN AnnounceCo-Marketing Agreement for RNAi Library with High-Content Cellular Screening System

  Xantos Biomedicine AG and QIAGEN N.V. announced their partnership for co-marketing QIAGEN's proprietary TOM-amidite chemistry based genome-wide RNAi products with Xantos' automated cell-based screening platform, XantoScreen(TM). By combining the capabilities of both companies' platforms customers wi more

• ALTANA Pharma and Atugen Renew Target Validation and License Agreement

  Atugen AG announced that it has renewed its non-exclusive Target Validation and License Agreement with ALTANA Pharma AG for another year. The agreement gives Altana the right to have molecular targets validated by Atugen's discovery team, utilizing a number of proprietary knockdown tools and transfe more

White papers Transfection

• Optimization of Transfection Conditions for the Human HL-60 Promyelocytic Leukemic T-Cell Line Using FuGENE® HD Transfection Reagent
  

  Transfection is commonly performed to introduce many different types of molecules (plasmid DNA, RNA, siRNA, miRNA) into eukaryotic cell lines. Once inside, these molecules can be expressed in a transient or a stable fashion. In the case of transient transfection, molecules do not integrate into the host cell genome and are only expressed for approximately 24 hours - 96 hours post-transfection. more

• Superiority of FuGENE® HD Transfection Reagent in Minimizing Non-Specific Cellular Interferon Responses
  

  Many viruses, including human cytomegalovirus (HCMV), encode for genes that can modulate or interfere with the ability of cells to mount an effective antiviral response to infection. Transfection of viral genes into cultures of mammalian cells is an important research tool to evaluate the function of viral gene products. We utilized this approach to identify viral genes involved in modulation of interferon (IFN)-mediated cell signaling pathways. more

• Superior Transfection of Human Embryonic Stem Cells with FuGENE® HD Transfection Reagent
  

  Gene manipulation techniques are potentially powerful tools in many applications for human embryonic stem (ES) cell research. Controlling expression levels of specific genes may improve the efficiency of differentiation induction. Cell types of interest may be collected using marker genes and antibiotic resistance genes. Tracking of ES cells derived after engraftment could be facilitated by tracer genes. It may also be possible to selectively destroy transplanted cells. more

Websites Transfection