Topic protein crystallization

News protein crystallization

• Dunn Labortechnik celebrates its 30th anniversary

  In 1982 the company Dunn Labortechnik was founded in Asbach (Germany) by Hannelore and Peter Dunn. Since then, the company has supplied research and routine laboratories with equipment, disposables as well as immunoreagents, plasma and sera and has evolved from a nationally to an internationally ope more

• QIAGEN and the JCSG Announce Agreement for Commercialization of Sample Technologies for Protein Crystallography

  QIAGEN N.V. has entered a strategic agreement with the Joint Center for Structural Genomics (JCSG), one of the 4 PSI Structural Genomics Production Centers, providing protein crystallographers with a new set of proven crystallization screens that have been assembled from analysis of hundreds of thou more

• Structure of Human Cytochrome P450 2D6 solved by GlaxoSmithKline with the use of Fludigm Technology

  The TOPAZ® system for protein crystallization was instrumental in helping GlaxoSmithKline (GSK) solve the structure of cytochrome P450 2D6, an enzyme important in the metabolism of a wide variety of drugs. TOPAZ crystallization chips were used to identify positive conditions for crystallization and more

White papers protein crystallization

• Automated Dynamic Light Scattering
  

  DLS analysis is a widely applied, non-invasive method for measuring the effective size of molecules in solution. This technique yields valuable information for the characterization of molecules and particles. It facilitates formerly laborious and time consuming measurements, e.g. screening for aggregates or determining optimal crystallization conditions for proteins. The Wyatt Plate Reader is the instrument of choice for any application where molecular size, stability and aggregation are of interest. It reads industry standard microplates with up to 1536 samples automatically and temperature-controlled, if desired. The applications of the technique are wide ranging and include many of the fastest growing areas of research - proteins, biomaterials, liposomes and micelles as well as the established uses for particle sizing and aggregation detection. Conscious of the numerous characterization challenges in the area of drug delivery systems and therapeutic antibodies more

• Measurement of Nano particles and Proteins
  

  Colloid emulsions in their native environment require particle size determination in high concentration since there are concerns about changes in sample morphology upon dilution eg break up of aggregates. For proteins and other samples with very low concentration and for weakly scattering samples high sensitivity is required. New technologies offer both. more

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