Syro Wave™ - Automated Microwave and Parallel Peptide Synthesizer

The Biotage^® Syro Wave™ system is the only programmable peptide synthesizer that is capable of both conventional room temperature parallel peptide synthesis and microwave assisted peptide synthesis. The system is fully automated and computer controlled utilizing a pipetting robot with a single arm.

The Syro Wave™ is a union of the Syro I and Biotage Initiator instruments, controlled by a single PC. The Intuitive Syro XP software controls the instrument functions and calculates all amounts and volumes of amino acids and reagents required. Each cycle of the synthesis can receive a completely different protocol. This flexibility allows not only single or multiple couplings, but also complete freedom in the choice of coupling strategies within any particular synthesis cycle.

Syro Wave™ offers the unique ability to make part of the peptide sequence using conventional solid phase peptide synthesis on the parallel reactor block and then transfer the reactor vial to the microwave cavity to drive difficult couplings to completion. With the Syro Wave™ peptide synthesizer, Biotage offers a system with a proven pedigree and history of performance and reliability, and a new addition to a range of peptide synthesis platforms utilizing either traditional room temperature or microwave technologies in both entry-level and high throughput configurations.

Advantages

• Microwave assisted peptide synthesis
• Parallel peptide synthesis
• Vortex mixing in microwave cavity
• Vortex mixing in reactor block
• Single robotic arm
• Disposable polypropylene reactor vials with PTFE frits
• Variable scale from 1-300 μmol
• Disposable amino acid containers
• Intuitive Syro XP software
• Off-line cleavage

Economically Synthesize Difficult Sequences

Use microwave irradiation and standard reagents to synthesize difficult sequences that are problematic or even impossible to synthesize using standard methods.

Save Time and Increase Productivity

Automated parallel operation allows for the synthesis of more peptides in shorter times resulting in the highest productivity. Reduce cycle times even further using microwave irradiation.

Increase Yield and Purity

Accurate dispensing of exact volumes of all reactants and vortexing of the reaction mixture, guarantee the optimal result in terms of yield and purity while minimizing waste and costs.

Detailed Reagent Calculation

The easy to use Syro XP software controls the instrument functions and calculates all amounts and volumes of amino acids and reagents required.

Reduce Coupling Costs

The use of a digital syringe pump and minimized flow paths lead to low amino acid and reagent consumption. This reduces coupling and running costs compared to other systems.

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