Malvern Instruments and Kaiser Optical Systems announced a development collaboration that will enhance the product portfolios of both companies. As part of the process of bringing the resulting new products to market, both companies will be seeking the involvement of potential customers at ... more
Raman Based PAT/QbD Analyzer for Process Development and Understanding
Kaiser RamanRXN2™ Hybrid Analyzer
The RamanRxn Systems™ suite of instruments has set the standard for analyzing, monitoring and controlling chemical processes since its introduction in 2000. Raman spectroscopy provides the chemical specificity of a mid-IR analyzer with the ease of sampling of a near-IR analyzer.
The RamanRxn2™ Hybrid analyzer is the latest advanced Raman analyzer from Kaiser to join the RamanRxn Systems™ suite. It features Hybrid (micron and mm) probe capability, high resolution, as well as transportability. The RamanRxn2™ Hybrid analyzer when combined with the latest version of the iC Raman™ software makes this analyzer the most advanced, flexible analyzer for Raman methods development and reaction analysis. The Raman spectrum contains features that are ideal for fast qualitative and robust quantitative analyses, often without the need for multivariate techniques.
Versatility was a key goal when developing the feature set for this analyzer. Millimeter to micron sampling versatility is accomplished by coupling the RamanRxn2™ Hybrid analyzer with either the MR Probe or the PhAT Probe probe heads for non-contact or direct insertion sampling. Standard on all RamanRxn2C™ models and available as an option for the RamanRxn2™ models is an ergonomic trolley including built-in probe and optic storage, a routine-analysis sample compartment, fiber storage, and the analyzer control system.
Best of Best Worlds
- mm to micron sampling
- Optimized liquids analysis mode
- Optimized solids analysis mode
- Qualitative and quantitative analysis
- Laboratory, scale-up, and pilot-plant compatible
RamanRxn2™ Hybrid Analyzer Applications
- Pharmaceutical formulations development: Blending, granulations, drying
- Pharmaceutical API development: Reaction chemistry, yield, form ID
- Polymer Blending
- Extrusion Monitoring
- Biologics / Biotech
The RamanRxn2™ Hybrid analyzer provides the capability of several different Raman analyzers in a single system. Equally capable of being a transportable raw materials identification analyzer, a bench-top analyzer for methods development in the lab, reaction monitoring in the pilot plant, process development for a wide array of unit operations in a manufacturing environment, or a dedicated quality control analyzer.
The RamanRxn2™ Hybrid fiber-coupled Raman analyzer serves the needs of the analytical Raman market, process analytics, chemical, and polymers markets as well as the pharmaceutical and biotech market. When combined with the latest compliant version of the iC Raman™ data acquisition software, the RamanRxn2™ Hybrid analyzer meets the needs of both GLP and GMP governed areas within the pharmaceutical industry for both PAT and QbD applications.
For manufacturing where analyzer wash down is required, Kaiser’s RamanRxn3™ models are available.
- 1Accelerated Solvent Extraction (ASE) – Maximize results and reduce errors in food analysis!
- 2Soxtec integrated total fat analysis
- 3GC/MS/MS - Identification. Quantitation. Technovation.
- 4Less is more: Highly accurate viscosity measurements from 0.1 mL of sample
- 5Autosampler for the fully automated Analysis of up to 84 Samples
- 6SPECORD® PLUS: The New Generation of Double-Beam Photometers from Analytik Jena
- 7State-of-the-art sample preparation for analytical laboratories. Safe, quick and efficient
- 8Automatic distillation systems for Kjeldahl analysis from FOSS
- 9Combining the precision of Bruker’s MALDI-TOF with the industry specific Accugenix® microbial database
- 10The most flexible Ion Chromatography System: High resolution, fast analysis high-pressure IC