Commercial aluminium foil could be used to help scientists understand more about important biological pathways. Hubert Girault, at the Federal Polytechnic School of Lausanne, Switzerland, and colleagues used the foil to extract multi-phosphorylated peptides from digested protein mixtures. Phosphory more
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Phosphoproteins no longer foil mass spectrometry
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Dot Products: Analytical Applications of Enzymatic Growth of Quantum Dots
The search for time and cost effective as well as sensitive methods for bioanalytical assays is currently of great interest. At the center of Biofunctional Nanomaterials in San Sebastian (Spain), Valery Pavlov and his co-workers are undertaking research in the area of the design and preparation of n more
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The Committee for Risk Assessment Agrees Opinions on Harmonised Classification and Labelling for Three Chemical Substances
The Committee for Risk Assessment (RAC) of ECHA has adopted opinions on the proposals for classification and labelling across Europe of three chemical substances as carcinogen, mutagen or toxic for reproduction The substances are: - Indium phosphide: The classification is currently not harmonised a more
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Detection of NADH and NADPH with the Omega's High Speed, Full UV/Vis Absorbance Spectrometer
Nicotinamide Adenine Dinucleotide (NAD+), reduced nicotinamide adenine dinucleotide (NADH), nicotinamide adenine dinucleotide phosphate (NADP+) and reduced nicotinamide adenine dinucleotide phosphate (NADPH) have been known to play vital roles in energy metabolism, antioxidation, and reductive biosynthesis. In recent years, these co-factors have been shown to be involved in other physiological functions as well, including aging, oxidative stress, intracellular calcium homeostasis, ROS production, cell death and gene expression. more
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Superiority of FuGENE® HD Transfection Reagent in Minimizing Non-Specific Cellular Interferon Responses
Many viruses, including human cytomegalovirus (HCMV), encode for genes that can modulate or interfere with the ability of cells to mount an effective antiviral response to infection. Transfection of viral genes into cultures of mammalian cells is an important research tool to evaluate the function of viral gene products. We utilized this approach to identify viral genes involved in modulation of interferon (IFN)-mediated cell signaling pathways. more
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New Silicone Technologies for Skin Care
In today's competitive skin care market, consumers look for a range of benefits, superior aesthetics and cost effectiveness. In response, formulators strive to create products that are multifunctional, easy to use and effective in small quantities. At the same time, the most successful products deliver benefits that stand out from those of the competition. Creams, lotions and color cosmetics must be easy to spread and comfortable to wear, without feeling tacky or greasy. Silicones have been popular ingredients in skin care products for more than fifty years. These versatile materials are known for their emolliency, wetting and spreading characteristics and ability to provide unique aesthetics. As technology continues to evolve, silicones increasingly offer multifunctional, high performance properties. This article reviews some of the newest silicone technologies available for the formulation of innovative skin care products more
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