29 Current news of Wiley-VCH
rssFluorescence lights up cells programmed to die
28-01-2013
Programmed cell death, or apoptosis, occurs tens of millions of times every day in every human body. Researchers in South Korea have devised an easy method to detect apoptotic cells by fluorescence, as they report in Chemistry—An Asian Journal. Their method makes it easier to detect improper ...
24-01-2013
Raman spectroscopy has recently undergone major advances in the area of deep non-invasive characterisation of biological tissues. The progress stems from the development of spatially offset Raman spectroscopy (SORS) and renaissance of transmission Raman spectroscopy permitting the assessment ...
Measuring proteins in real-time down to fM solution concentration levels
21-08-2012
Label free optical biosensors enable the monitoring of biomolecules and their interactions in often highly sensitive diagnostic assays. Several methods have been employed for this purpose, including Whispering Gallery Mode (WGM) biosensing, which offers a particularly sensitive approach to ...
04-06-2012
Coherent Raman scattering methods have one key advantage over spontaneous Raman microscopy: speed. The (sub-)microsecond pixel dwell times offered by narrowband CRS imaging methods have initiated a new era of chemical imaging applications in biology and biomedicine.Biomedical scientists are ...
Which pathways do nanomedicines take after they have been swallowed?
04-06-2012
Advances in pharmaceutical nanotechnology have yielded ever increasingly sophisticated nanoparticles for medicine delivery. When administered via oral, intravenous, ocular and transcutaneous delivery routes, these nanoparticles can elicit enhanced drug performance. One such recently developed ...
MRI systems with high relaxivities and long luminescence lifetimes also suitable for time-gated fluorescence imaging
19-03-2012
Accurate visualization of living systems is key to the correct diagnosis and effective treatment of many diseases, as well as an improved understanding of biological processes. Magnetic resonance imaging (MRI) is a popular non-invasive visualization technique, which requires a possibly toxic ...
09-03-2012
A biopsy is a painful and scarring but often unavoidable procedure, to decide whether a suspicious looking region on the skin is cancer or a harmless spot. Now, scientists attained promising results of autofluorescence and reflectance measurements of tissue as a noninvasive approach for basal ...
Fluorogenic Peptide-Based Substrates for Monitoring Thrombin Activity
24-02-2012
Thrombin plays a key role in various pathologies of the haemostatic system. Overexpression of thrombin can result in thrombosis, whereas its underexpression might lead to haemophilia. Therefore, accurate monitoring of thrombin activity is crucial for determining the proper treatment of a ...
07-02-2012
US scientists have synthesized a polymethine dye that can be used for fluorescence anisotropy imaging in the near-infrared (NIR) spectral range, making new in vivo applications of this technique possible. Until now, the method has been limited to the visible part of the spectrum, mainly being ...
Scientists develop the most advanced computer model to-date of the scattering of polarized light from chiral molecules
07-10-2011
An international research team has described the first calculations of Raman optical activity (ROA) spectra using coupled-cluster theory – one of the most reliable quantum chemical methods available. ROA is a valuable tool for the structural characterization of a wide range of molecules, ...
