21 Current news of TU München

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Single-neuron observations mark steps in Alzheimer's disease

04-25-2012

Studying a mouse model of Alzheimer's disease, neuroscientists at the Technische Universitaet Muenchen have observed correlations between increases in both soluble and plaque-forming beta-amyloid – a protein implicated in the disease process – and dysfunctional developments on several levels: ...

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New capabilities in single-molecule sensing

DNA origami puts a smart lid on solid-state nanopore sensors

04-24-2012

The latest advance in solid-state nanopore sensors – devices that are made with standard tools of the semiconductor industry yet can offer single-molecule sensitivity for label-free protein screening – expands their bag of tricks through bionanotechnology. Researchers at the Technische ...

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Aimed shot on single molecules

UV femtosecond laser pulses analyze internal dynamics of individual molecules

03-07-2012

Nowadays, large laser systems provide ultra-short light pulses of very high intensity, which – in principle – allow the imaging of matter and its dynamics on atomic scales, down to a single molecule or a virus. However, current methods fall short in efficiency to overlap a target molecule in ...

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Two world records at the FRM II: The world’s strongest and purest neutron beam

02-20-2012

The world’s strongest neutron beam is produced by a scientific instrument at the research neutron source FRM II (Forschungs-Neutronenquelle Heinz Maier-Leibnitz) at the Technischen Universitaet Muenchen (TUM). But that is not all: During the long maintenance break in 2011, the instrument PGAA ...

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Large conformational changes without ATP consummation

Energy saving chaperone Hsp90

01-18-2012

A special group of proteins, the so-called chaperones, helps other proteins to obtain their correct conformation. Until now scientists supposed that hydrolyzing ATP provides the energy for the large conformational changes of chaperone Hsp90. Now a research team from the Nanosystems Initiative ...

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The smallest conceivable switch

Targeted proton transfer within a molecule

12-15-2011

For a long time miniaturization has been the magic word in electronics. Dr. Willi Auwaerter and Professor Johannes Barth, together with their team of physicists at the Technische Universitaet Muenchen (TUM), have now presented a novel molecular switch in the journal Nature Nanotechnology. ...

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What's really in that luscious chocolate aroma?

08-31-2011

The mouth-watering aroma of roasted cocoa beans — key ingredient for chocolate — emerges from substances that individually smell like potato chips, cooked meat, peaches, raw beef fat, cooked cabbage, human sweat, earth, cucumber, honey and an improbable palate of other distinctly ...

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Ultra fast photodetectors out of carbon nanotubes

Speed detection of electrons in nanoscale photodetectors

03-14-2011

Carbon nanotubes have a multitude of unusual properties which make them promising candidates for optoelectronic components. However, so far it has proven extremely difficult to analyze or influence their optic and electronic properties. A team of researchers headed by Professor Alexander ...

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New method for unraveling molecular structures

Residual dipolar couplings unveil structure of small molecules

02-22-2011

Chemists at the Technische Universitaet Muenchen (TUM) and the Karlsruhe Institute of Technology (KIT) introduced a new method for identifying chemical compounds. The approach they used is an improvement on nuclear magnetic resonance (NMR) measurements – for decades one of the most successful ...

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New insights from the nano world: Direct observation of carbon monoxide binding

01-12-2011

Carbon monoxide is highly toxic since it blocks the binding site for oxygen in hemoglobin. This very principle – a porphyrin ring with a central iron or cobalt atom that the poisonous gas attaches to – can be used to implement sensors to warn against carbon monoxide. Physicists headed by ...

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