17 Current news of Cold Spring Harbor Laboratory
rss02-09-2010
Cellular imaging offers a wealth of data about how cells respond to stimuli, but harnessing this technique to study biological systems is a daunting challenge. In a study published in Genome Research, researchers have developed a novel method of interpreting data from single-cell images to ...
10-12-2009
If you have ever taken a long road trip, the windshield of your car will inevitably be splattered with bugs by the time you arrive at your destination. Could the DNA left behind be used to estimate the diversity of insects in the region? In a study published online in Genome Research, ...
07-14-2009
A group of researchers from the Cold Spring Harbor Laboratory (CSHL) and Agilent Technologies Inc. have developed a technique that complements massively parallel next-generation DNA sequencing, using custom microarrays to focus on genomic regions of high interest. The method, published in ...
'DNA Sudoku' pools multitude of DNA samples for sequencing in manner analogous to solving a Sudoku grid
06-30-2009
A math-based game that has taken the world by storm with its ability to delight and puzzle may now be poised to revolutionize the fast-changing world of genome sequencing and the field of medical genetics, suggests a new report by a team of scientists at Cold Spring Harbor Laboratory (CSHL). ...
06-09-2009
The woolly mammoth died out several thousand years ago, but the genetic material they left behind is yielding new clues about the evolution of mammals. In a study published online in Genome Research, scientists have analyzed the mammoth genome looking for mobile DNA elements, revealing new ...
10-02-2008
Our genome contains many genes encoding proteins that are similar to those of other organisms, suggesting evolutionary relationships; however, protein-coding genes account for only a small fraction the genome, and there are many other DNA sequences that are conserved across species. What are ...
Enzyme target, Brk, is shown to be an accelerator of HER2-positive tumors
08-27-2008
Tumor cells in a particular subset of breast cancer patients churn out too much of a protein called ErbB2 - also often called HER2 - which drives the cells to proliferate unchecked. Patients unlucky enough to be in this group - about one in four - have poorer prognoses and clinical outcomes ...
07-11-2008
Coat color of wild and domestic animals is a critical trait that has significant biological and economic impact. In a study published online in Genome Research, researchers have identified the genetic basis for black coat color, and white, in a breed of domestic sheep. In the wild, mammalian ...
04-11-2008
In the event of an outbreak or a bioterrorist attack, rapid identification of the genetic changes responsible for virulence or drug resistance is essential to mounting an effective response. Standard DNA sequencing and analysis of a pathogen genome is time-intensive and likely impractical ...
11-01-2007
A report that appears in the scientific journal Genome Research details the first assembly, annotation, and comparative analysis of the domestic cat genome (Felis catus). The DNA of a 4-year-old Abyssinian cat named Cinnamon, whose well-documented lineage can be traced back several ...
