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Stem cell divisions in the adult brain seen for the first time

12-Feb-2018

Scientists from the University of Zurich have succeeded for the first time in tracking individual stem cells and their neuronal progeny over months within the intact adult brain. This study sheds light on how new neurons are produced throughout life. The generation of new nerve cells was once ...

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Sticking sugar to protein

Researchers clarified the 3D structure of an important enzyme that links sugar to proteins – a breakthrough

09-Feb-2018

Whenever cells receive signals, interact with other cells or identify viruses and bacteria, the process involves not only proteins but also sugar chains attached to their surface. The subject of relatively little attention until now, these structures differ widely in composition and branching, ...

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Lab-on-a-chip for tracking single bacterial cells

02-Feb-2018

Researchers at the Biozentrum of the University of Basel, together with researchers from the Max Planck Institute in Dresden, have set up a novel lab-on-a-chip with accompanying automatic analysis software. As they report in Nature Communications, this integrated setup can be used to study gene ...

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Measuring molecular interactions

Previously unknown interactions between proteins and small metabolic molecules discovered

02-Feb-2018

ETH researchers have used a new approach to discover previously unknown interactions between proteins and small metabolic molecules in bacterial cells. The technique can also be used to test the effect of medications. Science now has a new “omics” – an interactomics, which deals with the ...

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The first precise measurement of a single molecule's effective charge

Discovery could pave the way to new diagnostic tools

16-Jan-2018

For the first time, scientists have precisely measured the effective electrical charge of a single molecule in solution. This fundamental insight of an SNSF Professor could also pave the way for future medical diagnostics. Electrical charge is one of the key properties that allows molecules to ...

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Extremely bright and fast light emission

12-Jan-2018

An international team of researchers from ETH Zurich, IBM Research Zurich, Empa and four American research institutions have found the explanation for why a class of nanocrystals that has been intensively studied in recent years shines in such incredibly bright colours. The nanocrystals contain ...

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New Biomarkers Predict Outcome of Cancer Immunotherapy

10-Jan-2018

Researchers at the University of Zurich have identified biomarkers in the blood that make it possible to predict whether cancer patients will respond positively to immunotherapy. Patients for whom therapy does not work can thus be treated using different methods at an earlier stage. Nowadays, ...

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A thermometer for the oceans

Measurement of noble gases in Antarctic ice cores

08-Jan-2018

The average sea temperature is an essential parameter of the global climate – but it is very difficult to measure. At least until now, because an international team of researchers including Empa scientists have now developed a novel method using the concentration of noble gases in the eternal ...

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Identifying the right target

Protein structure could unlock new treatments for cystic fibrosis

15-Dec-2017

Biochemists at the University of Zurich have used cryo-electron microscopy to determine the detailed architecture of the chloride channel TMEM16A. This protein is a promising target for the development of effective drugs to treat cystic fibrosis. Cystic fibrosis is a severe hereditary disease of ...

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Tracking Down Genetic Influences on Brain Disorders

28-Nov-2017

New findings will help to identify the genetic causes of brain disorders: researchers at the Universities of Basel, Bonn and Cologne have presented a systematic catalog of specific variable locations in the genome that influence gene activity in the human hippocampus. Individual differences in ...

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