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How to track and trace a protein: Nanosensors monitor intracellular deliveries

20-Jun-2018

Researchers at the University of Basel’s Biozentrum have developed a method for tracing the movement of proteins within the cell. They tagged proteins with tiny nanosensors, so-called nanobodies, which enable the scientists to live track and trace the proteins' pathway through the cell. The ...

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A nanotech sensor that turns molecular fingerprints into bar codes

11-Jun-2018

Infrared spectroscopy is the benchmark method for detecting and analyzing organic compounds. But it requires complicated procedures and large, expensive instruments, making device miniaturization challenging and hindering its use for some industrial and medical applications and for data ...

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Direct coupling of the Higgs boson to the top quark observed

06-Jun-2018

On 4 July 2012, two of the experiments at the CERN's Large Hadron Collider (LHC), ATLAS (A Toroidal LHC ApparatuS) and CMS (Compact-Muon-Solenoid), reported independently the discovery of the Higgs boson. The discovery confirmed the existence of the last missing elementary particle of the ...

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Individual impurity atoms detectable in graphene

17-Apr-2018

A team including physicists from the University of Basel has succeeded in using atomic force microscopy to clearly obtain images of individual impurity atoms in graphene ribbons. Thanks to the forces measured in the graphene’s two-dimensional carbon lattice, they were able to identify boron and ...

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Faster characterization of organic salts

27-Mar-2018

UZH researchers have developed a novel method that speeds up the process of determining crystal structures of organic salts and significantly reduces the effort required to do so. As about 40 percent of all active pharmaceutical ingredients are salts, this new crystallographic method is set to ...

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Recovery from spinal cord injuries can be predicted

09-Mar-2018

A trauma to the spinal cord, quickly leads to a progressive loss of nerve tissue. This not only affects the injured area, but over time affects also other parts of the spinal cord and even the brain. These neurodegenerative changes can be explored in detail using magnetic resonance imaging. An ...

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New tool for structural biology

New method of crystallising large membrane proteins

08-Mar-2018

ETH researchers have developed a new method of crystallising large membrane proteins in order to determine their structure. This will be of benefit to biological research and the pharmaceutical industry. Membrane-embedded proteins are an essential part of cells and any form of life. They not only ...

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Stem cell divisions in the adult brain seen for the first time

12-Feb-2018

Scientists from the University of Zurich have succeeded for the first time in tracking individual stem cells and their neuronal progeny over months within the intact adult brain. This study sheds light on how new neurons are produced throughout life. The generation of new nerve cells was once ...

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Sticking sugar to protein

Researchers clarified the 3D structure of an important enzyme that links sugar to proteins – a breakthrough

09-Feb-2018

Whenever cells receive signals, interact with other cells or identify viruses and bacteria, the process involves not only proteins but also sugar chains attached to their surface. The subject of relatively little attention until now, these structures differ widely in composition and branching, ...

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Lab-on-a-chip for tracking single bacterial cells

02-Feb-2018

Researchers at the Biozentrum of the University of Basel, together with researchers from the Max Planck Institute in Dresden, have set up a novel lab-on-a-chip with accompanying automatic analysis software. As they report in Nature Communications, this integrated setup can be used to study gene ...

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