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Potent, puzzling and (now less) toxic: How antifungal drug works

17-04-2014

Scientists have solved a decades-old medical mystery – and in the process have found a potentially less toxic way to fight invasive fungal infections, which kill about 1.5 million people a year. The researchers say they now understand the mechanism of action of amphotericin, an antifungal drug ...

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Nano shake-up

UD researchers demonstrate that processing can affect size of nanocarriers for targeted drug delivery

16-04-2014

Significant advances have been made in chemotherapy over the past decade, but targeting drugs to cancer cells while avoiding healthy tissues continues to be a major challenge. Nanotechnology has unlocked new pathways for targeted drug delivery, including the use of nanocarriers, or capsules, that ...

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New technique to sharpen microscope images

15-04-2014

The complexity of biology can befuddle even the most sophisticated light microscopes. Biological samples bend light in unpredictable ways, returning difficult-to-interpret information to the microscope and distorting the resulting image. New imaging technology developed at the Howard Hughes ...

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No compromises: Short, flexible, reusable AFM probe

11-04-2014

JILA researchers have engineered a short, flexible, reusable probe for the atomic force microscope (AFM) that enables state-of-the-art precision and stability in picoscale force measurements. Shorter, softer and more agile than standard and recently enhanced AFM probes, the JILA tips will benefit ...

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Toward a faster way to diagnose stroke

11-04-2014

When someone suffers from a stroke, a silent countdown begins. A fast diagnosis and treatment can mean the difference between life and death. So scientists are working on a new blood test that one day could rapidly confirm whether someone is having a stroke and what kind. Their report appears in ...

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Sustainable production of pharmaceutical compounds

SmartCell project: Novel plant biotechnology

10-04-2014

European scientists have made ground-breaking discoveries for improving the efficiency of the production of pharmaceuticals through plant biotechnology. Biotechnological production offers a cost-effective and environmentally friendly alternative to the chemical synthesis of rare and complex ...

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Scientists disagree on responsible research

10-04-2014

Responsible research has been put firmly on the political agenda with, for instance, EU's Horizon 2020 programme in which all research projects must show how they contribute responsibly to society. New research from the University of Copenhagen reveals that the scientists themselves place great ...

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Amino acid fingerprints revealed in new study

08-04-2014

Some three billion base pairs make up the human genome—the floor plan of life. In 2003, the Human Genome Project announced the successful decryption of this code, a tour de force that continues to supply a stream of insights relevant to human health and disease. Nevertheless, the primary actors ...

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Going global

Stowers team reports genome-wide analysis of genes that drive cell division in a multicellular organism

04-04-2014

In textbooks, the grand-finale of cell division is the tug-of-war fought inside dividing cells as duplicated pairs of chromosomes get dragged in opposite directions into daughter cells. This process, called mitosis, is visually stunning to observe under a microscope. Equally stunning to cell ...

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Simple microfluidic devices now have valves

04-04-2014

Researchers at the National Institute of Standards and Technology (NIST) have added yet another innovation—miniature valves—to their ever-growing collection of inexpensive, easy-to-manufacture and highly efficient microfluidic devices made from plastic films and double-sided tape. Traditionally, ...

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