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New insights into the function of the main class of drug targets

05-Feb-2016

About thirty percent of all medical drugs such as beta-blockers or antidepressants interact with certain types of cell surface proteins called G protein coupled receptors. In collaboration with researchers from the Paul Scherrer Institute, the group of Prof. Stephan Grzesiek at the Biozentrum of ...

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Microscopy: Nine at one blow

05-Feb-2016

Advance in biomedical imaging: The University of Würzburg's Biocenter has enhanced fluorescence microscopy to label and visualise up to nine different cell structures simultaneously. Fluorescence microscopy allows researchers to visualise biomolecules in cells. They label the molecules using ...

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'Gene fusion' mutation uses 3-way mechanism to drive childhood brain cancers

04-Feb-2016

A powerful, three-way mechanism by which a mutation drives the growth of childhood brain cancers, was discovered by scientists from the Perelman School of Medicine at the University of Pennsylvania and The Children's Hospital of Philadelphia (CHOP). The team hopes the discovery will lead to ...

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Suitable Protein Tags for Nanoscopy

02-Feb-2016

Modern optical technologies such as super-resolution nanoscopy enable to exactly image small structures and molecular processes, therefore, providing a fascinating view into living cells. To visualize such processes in the nanometer range, cellular structures of interest have to be efficiently ...

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The device with the fine nose

02-Feb-2016

When it comes to measuring the smallest traces of volatile chemical compounds in the air, the analysis devices in Pablo Sinues' laboratory are among the most sensitive in the world. They can find the proverbial needle in a haystack: the detection limit for airborne volatile compounds is around a ...

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Identifying Another Piece in the Parkinson's Disease Pathology Puzzle

International Consortium Identifies and Validates Cellular Role of Priority Parkinson’s Disease Drug Target, LRRK2 Kinase

01-Feb-2016

An international public-private research consortium has identified and validated a cellular role of a primary Parkinson’s disease drug target, the LRRK2 kinase. This important finding illuminates a novel route for therapeutic development and intervention testing for Parkinson’s, the second most ...

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Sweating for science

Wearable device detects, analyzes real-time changes in chemical composition of sweat

29-Jan-2016

A team of researchers has combined two separate technologies to create a health-monitoring device that is noninvasive, doesn't interfere with strenuous outdoor activities and can continuously track a user's health at the molecular level. The two-part system of flexible sensors and a flexible ...

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Drugs and other contaminants found in private drinking wells on Cape Cod

29-Jan-2016

Recent news about tainted water in Flint, Michigan, and other parts of the country have called into question the safety of the nation's drinking water supply. Adding to this, a new study finds that pollutants from household wastewater--pharmaceuticals and consumer product chemicals--can make ...

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New patent on fast measurements in liquids

27-Jan-2016

A new invention will open the doors for an entirely new way of measuring properties within liquids. The invention, a sol-gel matrix, will make it possible to perform measurements that are reliable, incredibly rapid and can be conducted over extended periods of time. The development will be a boon ...

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New study creates first 3-D vision of cancer target

27-Jan-2016

A team from the University of Leicester has for the first time published a detailed description of a protein linked to many types of cancer. The lab-based study from the Department of Molecular and Cell Biology now provides an opportunity for scientists to develop drugs to target this protein. Dr ...

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