Tecan and the Monash Antibody Technologies Facility join forces to produce monoclonal antibody production facility

07-04-2007: Tecan and the Monash Antibody Technologies Facility (MATF) at Monash University, Australia, have announced a partnership to create one of the largest, most sophisticated monoclonal antibody production systems in the world. Plans are already underway to develop the system, which will be based around multiple, integrated liquid handling workstations and will fully automate all the stages of the production process.

In the research world, the use of monoclonal antibodies has proven crucial to the understanding of a myriad of physiological processes, and has led to new approaches in the treatment of diseases with great unmet clinical need. In the medical world, they are currently used as diagnostic agents to detect cancers or infectious diseases; as vaccines to boost the body's immune response; and as therapeutics, to target cancerous cells or to decrease the body's own immune response in diseases such as rheumatoid arthritis and multiple sclerosis.

The MATF is one of the only high throughput production facilities in the world offering custom-made, high-affinity monoclonal antibodies. The new system will increase the production capacity at MATF from original estimates of 500 panels of novel antibodies a year to potentially 5,000, helping to alleviate the bottleneck of antibody supply experienced by many researchers working on protein function and physiological processes.

The new system, partially funded by the Victorian State Government and Monash University, National Collaborative Research Infrastructure Strategy and the Australian Stem Cell Centre, is the first major step towards an extensive assay development program planned for 2008, which will further strengthen Monash University's rising profile as a centre of excellence in the international medical research community.

Tecan's team of experienced application specialists and engineers will build the new system at the company's headquarters in Männedorf, Switzerland, ready for installation at the MATF in April 2008.