For the first time ever, scientists have captured images of terahertz electron dynamics of a semiconductor surface on the atomic scale. The successful experiment indicates a bright future for the new and quickly growing sub-field called terahertz scanning tunneling microscopy (THz-STM), pio ... more
Detecting bacteria on paper
Scientists in Canada have developed a low-cost, portable, paper-based device for detecting antibiotic-resistant bacteria that could be used in the field in remote areas to characterise infectious diseases and assess food and water quality.
The scientists used a paper support to hold wax-patterned paper culture media, covered by a clear plastic window. To test their device, they placed two ‘zones’ of antibiotics on to the media then added a blue dye and a bacteria sample, E. coli, on top of the dye.
After sealing and incubating the device overnight, the researchers observed, through the plastic window, that areas that had no bacterial growth remained blue and areas where the bacteria had successfully grown had turned pink. The size of the blue areas around the antibiotic zones indicates the susceptibility of the bacteria to antibiotic treatment. A system of a pattern of uniform hydrophobic spots across the media allows this blue area to be measured to quantify this antibiotic susceptibility.
The team also showed that the paper device could be easily stored over a long period of time. After assembling to the point that it contained the culture media and antibiotics, it could be left for up to 70 days in a sealed bag. The long-term storage, ease of use and cheap components required to make the device make it very promising for in-field use.
- infectious diseases
- water quality
- culture media
- University of Alberta
An interdisciplinary team of engineering and pharmaceutical researchers at the University of Alberta has invented a device that can rapidly identify harmful bacteria and can determine whether it is resistant to antibiotics. The device could save precious hours in patient care and public hea ... more
A garnet crystal only one micrometre in diameter was instrumental in a University of Alberta team of physicists creating a route to "lab-on-a-chip" technology for magnetic resonance, a tool to simplify advanced magnetic analysis for device development and interdisciplinary science. "To most ... more
Scientists in Canada and the United States have developed a chip sensor for monitoring how drug candidates alter amyloid-β peptide aggregation that they hope could be used to find new treatments for Alzheimer’s disease. Research into Alzheimer’s disease has shown that the self-aggregation o ... more
Scientists in the UK have developed a new class of MRI (magnetic resonance imaging) agents that promise to deliver clearer images more quickly. Chemical shifts from proton NMR normally fall between 0-12ppm, but water and fat resonate at 4.7 and 1.3ppm respectively, causing noise that can ov ... more
Scientists in China have developed a simple microchip that enables quick and inexpensive high-throughput screening of potential drug candidates in 3D cell cultures. Scientists often use cell-based high-throughput screening in the first stage of drug design as a technique to quickly identify ... more
Conference30-08 – 01-09
This meeting aims to set the agenda for the surface-enhanced Raman scattering (SERS) field for the next 10 years, by bringing the community together to welcome in new emerging priority areas and embracing the diversity of approaches and disciplines which are contributing to the growth and u ... more
- 1Insight into enzyme's 3-D structure could cut biofuel costs
- 2Sensors detect disease markers in breath
- 3Plasmon-powered upconversion nanocrystals for enhanced bioimaging and polarized emission
- 4Taking a closer look at genetic switches in cancer
- 5A fresh look inside the protein nano-machines
- 6The stickiness of molecules
- 7Discovery of a key regulatory gene in cardiac valve formation