UAlberta chemistry professor Robert Campbell is developing new ways to see and manipulate the activity of neurons in the brain, which could revolutionize the way we understand the organ that controls most of the activities of the body. "We want to help other researchers apply these new neur ... more
Detecting bacteria on paper
Scientists in Canada have developed a low-cost, portable, paper-based device for detecting antibiotic-resistant bacteria that could be used in the field in remote areas to characterise infectious diseases and assess food and water quality.
The scientists used a paper support to hold wax-patterned paper culture media, covered by a clear plastic window. To test their device, they placed two ‘zones’ of antibiotics on to the media then added a blue dye and a bacteria sample, E. coli, on top of the dye.
After sealing and incubating the device overnight, the researchers observed, through the plastic window, that areas that had no bacterial growth remained blue and areas where the bacteria had successfully grown had turned pink. The size of the blue areas around the antibiotic zones indicates the susceptibility of the bacteria to antibiotic treatment. A system of a pattern of uniform hydrophobic spots across the media allows this blue area to be measured to quantify this antibiotic susceptibility.
The team also showed that the paper device could be easily stored over a long period of time. After assembling to the point that it contained the culture media and antibiotics, it could be left for up to 70 days in a sealed bag. The long-term storage, ease of use and cheap components required to make the device make it very promising for in-field use.
- infectious diseases
- water quality
- culture media
- University of Alberta
For the first time ever, scientists have captured images of terahertz electron dynamics of a semiconductor surface on the atomic scale. The successful experiment indicates a bright future for the new and quickly growing sub-field called terahertz scanning tunneling microscopy (THz-STM), pio ... more
An interdisciplinary team of engineering and pharmaceutical researchers at the University of Alberta has invented a device that can rapidly identify harmful bacteria and can determine whether it is resistant to antibiotics. The device could save precious hours in patient care and public hea ... more
Scientists in Canada and the United States have developed a chip sensor for monitoring how drug candidates alter amyloid-β peptide aggregation that they hope could be used to find new treatments for Alzheimer’s disease. Research into Alzheimer’s disease has shown that the self-aggregation o ... more
Scientists in the UK have developed a new class of MRI (magnetic resonance imaging) agents that promise to deliver clearer images more quickly. Chemical shifts from proton NMR normally fall between 0-12ppm, but water and fat resonate at 4.7 and 1.3ppm respectively, causing noise that can ov ... more
Scientists in China have developed a simple microchip that enables quick and inexpensive high-throughput screening of potential drug candidates in 3D cell cultures. Scientists often use cell-based high-throughput screening in the first stage of drug design as a technique to quickly identify ... more
- 1Next generation of neuroscience tools
- 2Sartorius Campus expands: Official opening of the new manufacturing facility for laboratory instruments
- 3Ultrafast snapshots of relaxing electrons in solids
- 4New method for identifying carbon compounds derived from fossil fuels
- 5A spectroscopic 'science camera' system for smartphones
- 6Liquid cats, disgust for cheese and reversed genitalia
- 7How does a cell maintain its identity during replication?
- 8New genetic cause discovered for photosensitive blood disorder
- 9Transplanted hearts reveals risk gene for cardiovascular disease
- 10Toxic chemicals in building materials even in "green housing"