08-03-2011: A reusable, natural and cheap amylose-functionalised graphene sensor was developed for highly sensitive and visual fluorescent chiral sensing by a team in China.
The team found that the sensor’s detection sensitivity toward L-tryptophan was over 100 times higher than that of recently reported electrochemical sensors and colorimetric sensors. In comparison with commonly used DNA or peptides as a probe, natural amylose is more attractive because it’s cheap, readily available, simple to manipulate and is reusable.
The specific selectivity for tryptophan enantiomers towards other essential amino acids allows potential chiroselective analysis of tryptophan in complex samples such as biological fluids. This design can, in principle, be implemented for other target molecules that can form an inclusion complex with amylase, say the researchers.
Original publication:
W Wei, K Qu, J Ren and X Qu, Chem. Sci., 2011.
Materials: The first graphene-based chiral sensor
A reusable, natural and cheap amylose-functionalised graphene sensor was developed for highly sensitive and visual fluorescent chiral sensing by a team in China.The team found that the sensor’s detection sensitivity toward L-tryptophan was over 100 times higher than that of recently reporte ... more
New X-ray technique distinguishes between that which previously looked the same
Traditional X-ray images can clearly distinguish between bones and soft tissue, with muscles, cartilage, tendons and soft-tissue tumours all look virtually identical. The phase-contrast technique developed a few years ago at the Paul Scherrer Institute enables X-ray images to be produced th ... more
A collaboration of scientists from various Beijing institutes, have made a pH-switchable, DNA-quantum dot hybrid that can also generate a photocurrent depending on the pH, allowing DNA to change conformation from a quadruplex to a double strand. Zhiyong Tang, Dongsheng Liu and colleagues f ... more
Materials: The first graphene-based chiral sensor
A reusable, natural and cheap amylose-functionalised graphene sensor was developed for highly sensitive and visual fluorescent chiral sensing by a team in China.The team found that the sensor’s detection sensitivity toward L-tryptophan was over 100 times higher than that of recently reporte ... more
Non-invasive tool to diagnose endometriosis
British scientists have used infrared spectroscopy to identify biochemical differences between endometrial tissue growing outside the uterus (ectopic) and the endometrial tissue of the uterus (eutopic). They also compared the results with tissue from endometriosis-free women (benign eut ... more
Sensor to search for artery hardening compounds in blood
A water-soluble zinc-based fluorescent sensor to detect pyrophosphate in blood has been developed by scientists from China. Pyrophosphate plays an important role in metabolic processes in the body but a lack of the compound can lead to Mönckeberg’s arteriosclerosis – calcium deposits in art ... more
How much caffeine is in your coffee?
Substantial differences exist in the caffeine and chlorogenic acid contents of espresso coffees that can result in over-consumption by consumers at risk of caffeine toxicity, say scientists in the UK. The team carried out high performance liquid chromatography analysis of 20 commercial espr ... more
Materials: The first graphene-based chiral sensor
A reusable, natural and cheap amylose-functionalised graphene sensor was developed for highly sensitive and visual fluorescent chiral sensing by a team in China.The team found that the sensor’s detection sensitivity toward L-tryptophan was over 100 times higher than that of recently reporte ... more
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