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• Pitt researchers coax gold into nanowires

  Researchers at the University of Pittsburgh have coaxed gold into nanowires as a way of creating an inexpensive material for detecting poisonous gases found in natural gas. Along with colleagues at the National Energy Technology Laboratory (NETL), Alexander Star, associate professor of chemistry in more

• University of Virginia researchers uncover new catalysis site
  

  Mention catalyst and most people will think of the catalytic converter, an emissions control device in the exhaust system of automobiles that reduces pollution. But catalysts are used for a broad variety of purposes, including the conversion of petroleum and renewable resources into fuel, as well as more

• New imaging technique accurately finds cancer cells, fast

  The long, anxious wait for biopsy results could soon be over, thanks to a tissue-imaging technique developed at the University of Illinois. The research team demonstrated the novel microscopy technique, called nonlinear interferometric vibrational imaging (NIVI), on rat breast-cancer cells and tissu more

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• Field-Flow Fractionation - The Universal Separation Principle for Particle and Macromolecule Characterization
  

  High molecular weight polymers, bio molecules or particles in a range of a few nanometers up to several microns are more and more important in science and technology. Many applications are based on the specific properties of these materials. For this reason, an exact knowledge of the molar mass or particle sizes distribution is essential for later application as well as for optimization of the production processes or quality control. In addition the knowledge about the chain structure of macromolecules or biopolymers as well as about the shape of particles is often necessary. For this reason those samples, which often can be very complex systems, have to be separated according to parameters such as e.g. hydrodynamic volume or molecular weight. After the separation process the resulting narrow dispersed fractions are detected with different techniques. more

• Quantitative Detection of Legionella pneumophila in Water Samples: Assay Transfer to the LightCycler® 480 Real-Time PCR System
  

  An assay to detect and quantify Legionella spp. in water samples was successfully transferred from a capillary-based LightCycler® Instrument to the novel multiwell plate-based LightCycler® 480 System. A previously described protocol was easily adapted by modifying the fluorescent label of the detection probe to match the filter set of the LightCycler® 480 Instrument. While reproducibility and analytical sensitivity of the assay were found to be comparable on both systems, the novel plate-based instrument allowed for higher sample throughput and reduced assay time per sample. more

• LOOXSTER® concentrates bacterial DNA
  

  Detection of the bacterial content of a specific sample, irrelevant from its source, is not as straightforward as it seems. In clinical microbiology laboratories, the gold standard method for the detection of pathogens in patients suspected of systemic infections is the blood culture. However, this technique is known to have many drawbacks especially with regard to patient's antibiotics treatment, low abundance and non-cultivable organisms. Moreover, it takes usually 3 to 5 days to obtain a result from blood culture which is too late to initiate proper antibiotic therapy. Amplification-based methods such as PCR allow results in a more rapid fashion. However, their sensitivity, to date, are no better, and sometimes worse, than culture-based methods. more

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