Genomes

News Genomes

  • Going global

    In textbooks, the grand-finale of cell division is the tug-of-war fought inside dividing cells as duplicated pairs of chromosomes get dragged in opposite directions into daughter cells. This process, called mitosis, is visually stunning to observe under a microscope. Equally stunning to cell biologi more

  • Tracing how the embryo takes over

    Embryonic development is initially controlled by maternal genetic information stored in the egg. LMU researchers now describe a methodology that allows the succeeding activation of the zygotic genome to be mapped at high resolution. In multicellular organisms, the earliest steps in embryonic develop more

  • New sequencing tools give up close look at yeast evolution

    The baker's yeast Saccharomyces cerevisiae has been associated with human activities for thousands of years, being the primary biological agent in baking, brewing, winemaking and other fermentation processes. It is also one of the most important model organisms in molecular biology and genetics rese more

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White papers Genomes

  • The New Genome Sequencer FLX System

    In 2005, the Genome Sequencer 20 System was introduced into the global life science market. Based on the revolutionary 454 sequencing technology, this system is able to generate hundreds of thousands of sequence reads in a few hours at a fraction of costs compared with the traditional Sanger technology. more

  • Real-Time PCR Quantification of Plant miRNAs Using Universal ProbeLibrary Technology

    MicroRNAs (miRNAs) are naturally occurring, highly conserved families of transcripts (18-25 nt in length) that are processed from larger hairpin precursors. Both plant and animal genomes encode miRNAs, and to date, there are over 4000 mature miRNA transcripts annotated. Although miRNAs represent a relatively abundant class of transcripts, their expression levels vary greatly among species and tissues. Less abundant miRNAs routinely fail detection using technologies such as cloning, northern hybridization and microarray analysis. Here, we present a real-time quantification method for accurate, sensitive, and economical detection of plant miRNAs based upon the stem-loop RT primer approach using an miRNA-specific primer coupled with a stem-loop specific Universal ProbeLibrary (UPL) probe. This approach represents a highly specific, sensitive, and easy-to-apply system to detect miRNAs. more

  • Metagenomics Analysis Using the Genome Sequencer FLX System

    The Genome Sequencer FLX System from 454 Life Sciences and Roche Applied Science is a versatile sequencing platform suitable for a wide range of applications, including de novo sequencing and assembly of genomic DNA, transcriptome sequencing, small RNA analysis, and amplicon sequencing. The Genome Sequencer FLX is built upon 454 Sequencing technology that enables long read lengths and very high single-read accuracy. One application in which the technology is accelerating the field's understanding is metagenomics. more

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Roche NimbleGen | Home

    Products Technology Support Contact News Company   Sequence Capture Enrich thousands of targeted loci from complex genomic DNA with programmable Sequence Capture microarrays for sequencing on the GS FLX Sequencer from 454 Life Sciences.   CGH Measure DNA copy number differences between a test an more

Genovoxx GmbH

GenoVoxx GmbH Company | Technology | Products | Patents | News & Events | Contact us Company Profile Genovoxx is developing a new sequencing technology based on massively parallel single molecule analysis (AnyGene.Technology TM ). Inspired by the idea of analysing complete genomes within hours, the more

Alios: Technology

Home About Us Overview Management Team Board of Directors Scientific Advisory Board Assay Development, Biochem Technology Activators of innate immunity Phosphate Protected Nucleotide Prodrugs Hyperglycosylated Type I Interferons News Room Press Releases Scientific Publications Careers Contact Contac more

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