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  • Biochemist developed way to silence genes that cause diseases

    Thanks to the ground-breaking research of 47-year-old German biochemist Thomas Tuschl, silencing genes is no longer a utopia. His method of switching off human genes is the basis for promising therapies to treat genetic disorders that trigger serious conditions such as haemophilia, amyloidosis, andp more

  • New gene responsible for cleft lip and palate syndrome identified

    An international team led by researchers from Karolinska Institutet in Sweden has identified a new gene related to the Van der Woude syndrome, the most common syndrome with cleft lip and palate. The study is published in the scientific periodical American Journal of Human Genetics and can lead the w more

  • Gene found to be crucial for formation of certain brain circuitry

    Using a powerful gene-hunting technique for the first time in mammalian brain cells, researchers at Johns Hopkins report they have identified a gene involved in building the circuitry that relays signals through the brain. The gene is a likely player in the aging process in the brain, the researcher more

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  • Real-Time PCR Quality Control for Gene Expression

    Quantitative real-time PCR (qPCR) has become the de facto standard for nucleic acid quantification. This achievement is due in large part to its sensitivity, specificity, accuracy, large dynamic range of linear quantification, and its speed. The qPCR technology has matured to a ready-to-use commonly available method in most molecular biology laboratories. Nevertheless, the reliability of the final quantification result depends heavily on all elements in the workflow, such as the quality of the input template (integrity and absence of inhibitors), the PCR assay (specificity, efficiency, limit of detection), and normalization strategy (validated reference genes). more

  • The New Genome Sequencer FLX System

    In 2005, the Genome Sequencer 20 System was introduced into the global life science market. Based on the revolutionary 454 sequencing technology, this system is able to generate hundreds of thousands of sequence reads in a few hours at a fraction of costs compared with the traditional Sanger technology. more

  • Fugene® HD Transfection Reagent: Superior Performance for Challenging Expression Studies

    The ability to efficiently introduce foreign molecules into cells constitutes an important tool in any laboratory and facilitates studies of gene regulation and protein function. A plethora of transfection methods have been developed for transfer of DNA into mammalian and animal cells. Those methods either utilize the physicochemical properties of the vector-carrier of the DNA or use mammalian viruses. In the first group of methods, some classic techniques are well-known, such as: calcium phosphate, DEAE-dextran, electroporation liposome-mediated delivery, direct microinjection/biolistic particle delivery, and non-liposomal multi-component reagents. Viral vector systems use both DNA (Adeno-) and RNA (Retro-, Lenti-) viruses. more

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    Products Technology Support Contact News Company   Sequence Capture Enrich thousands of targeted loci from complex genomic DNA with programmable Sequence Capture microarrays for sequencing on the GS FLX Sequencer from 454 Life Sciences.   CGH Measure DNA copy number differences between a test an more

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