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  • New sequencing reveals genetic history of tomatoes

    An international team of researchers, led by the Chinese Academy of Agricultural Sciences in Beijing, published in the journal Nature Genetics a brief genomic history of tomato breeding, based on sequencing of 360 varieties of the tomato plant. The C.M. Rick Tomato Genetics Resource Center at UC Dav more

  • Fly genome could help us improve health and our environment

    The house fly might be a worldwide pest, but its genome will provide information that could improve our lives. From insights into pathogen immunity, to pest control and decomposing waste, the 691 Mb genome has been sequenced and analyzed by a global consortium of scientists, and is published in the more

  • Gibbon genome sequenced

    An international team of researchers that includes Christian Roos, Markus Brameier and Lutz Walter from the German Primate Center (DPZ) in Göttingen, have decoded the genome of gibbons from Southeast Asia. With this, the entire genetic information of five different species of this primate family has more

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  • siRNA Silencing of Lamin A and Quantification of the Knockdown Effect via qPCR

    Lamins are structural proteins which form a thin fibrous layer called the nuclear lamina. Currently, three types of lamins are known in mammalian cells: lamin A, B, and C. Lamins may be involved in DNA replication, chromatin organization, differentiation, nuclear structural support, nuclear envelope reassembly, and several other processes. Mutations of lamin A can cause muscular dystrophy, dilated cardiomyopathy, familiar partial lipodystrophy [3], and other disorders. For the detailed analysis of the different functions of this more than 70 kDa large protein, the expression should be blocked. more

  • Genotypes in Smokers: Correlations with Smoking Behavior

    Smoking behavior is influenced by both genetic and environmental factors. Moreover, smoking initiation and smoking persistence have a heritability of at least 50%. A large body of work has been dedicated to associating multiple genetic markers of neurobiological pathways previously linked to addiction and smoking such as the central dopaminergic, serotoninergic, and nicotinergic pathways with different aspects of smoking behavior. In order to investigate the feasability of future genetic analyses, we genotyped 14 SNPs in 288 samples of addicted smokers using the LightCycler® 480 System with HybProbe assays. more

  • Enabling Cancer Research with FuGENE® HD Transfection Reagent

    A major problem in some areas of cancer research is the difficulty of transfecting a significant number of the cells of interest, while minimizing the cytotoxic or other off-target effects of the transfection event itself. It is well-known that the use of some transfection reagents results in high levels of expression of the gene of interest in surviving cells, but also in high levels of cell death or other cellular alterations. FuGENE® HD Transfection Reagent overcomes these problems, results in high ­levels of transfection in many cancer cell lines, and thus enables researchers to conduct experiments that have previously not been possible. more

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    Products Technology Support Contact News Company   Sequence Capture Enrich thousands of targeted loci from complex genomic DNA with programmable Sequence Capture microarrays for sequencing on the GS FLX Sequencer from 454 Life Sciences.   CGH Measure DNA copy number differences between a test an more

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