Genes

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  • Biochemist developed way to silence genes that cause diseases

    Thanks to the ground-breaking research of 47-year-old German biochemist Thomas Tuschl, silencing genes is no longer a utopia. His method of switching off human genes is the basis for promising therapies to treat genetic disorders that trigger serious conditions such as haemophilia, amyloidosis, andp more

  • New gene responsible for cleft lip and palate syndrome identified

    An international team led by researchers from Karolinska Institutet in Sweden has identified a new gene related to the Van der Woude syndrome, the most common syndrome with cleft lip and palate. The study is published in the scientific periodical American Journal of Human Genetics and can lead the w more

  • Gene found to be crucial for formation of certain brain circuitry

    Using a powerful gene-hunting technique for the first time in mammalian brain cells, researchers at Johns Hopkins report they have identified a gene involved in building the circuitry that relays signals through the brain. The gene is a likely player in the aging process in the brain, the researcher more

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  • Improved Performance of the LightCycler®

    Real-time reverse transcription-PCR (RT-PCR) is con­sidered the method of choice for any experiments requiring­ sensitive, specific, and reproducible quantification of mRNA molecules of interest. It is an essential tool for basic research, molecular medicine, and biotechnology. more

  • Fugene® HD Transfection Reagent: Superior Performance for Challenging Expression Studies

    The ability to efficiently introduce foreign molecules into cells constitutes an important tool in any laboratory and facilitates studies of gene regulation and protein function. A plethora of transfection methods have been developed for transfer of DNA into mammalian and animal cells. Those methods either utilize the physicochemical properties of the vector-carrier of the DNA or use mammalian viruses. In the first group of methods, some classic techniques are well-known, such as: calcium phosphate, DEAE-dextran, electroporation liposome-mediated delivery, direct microinjection/biolistic particle delivery, and non-liposomal multi-component reagents. Viral vector systems use both DNA (Adeno-) and RNA (Retro-, Lenti-) viruses. more

  • Ultrafast De Novo Sequencing of Corynebacterium urealyticum Using the Genome Sequencer 20 System

    A microbial genome sequence provides a wealth of data and specific information that cannot be obtained by other experimental approaches. A genome sequence can be regarded as the starting point for detailed bioinformatics analysis, metabolic reconstruction and systematic functional examination of all identified genes. In particular, genome sequencing has revealed important information on genes and deduced proteins of human pathogens, including putative virulence factors and potential new drug targets. more

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    Products Technology Support Contact News Company   Sequence Capture Enrich thousands of targeted loci from complex genomic DNA with programmable Sequence Capture microarrays for sequencing on the GS FLX Sequencer from 454 Life Sciences.   CGH Measure DNA copy number differences between a test an more

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