Fluorescence microscopy gives researchers incredible power to illuminate the tiniest structures and capture the real-time activities of live cells by tagging biological molecules with a veritable rainbow of fluorescent dyes. This power comes at a cost: The technology can be expensive and time-consum more
Fluorescence microscopy on a chip -- no lenses required
New dyes detect disease through heartbeat signals
Vibrant tones of yellow, orange, and red move in waves across the screen. Although the display looks like psychedelic art, it's actually providing highly technical medical information -- the electrical activity of a beating heart stained with voltage-sensitive dyes to test for injury or disease. The more
Seeing DNA 'blink'
Many of the secrets of cancer and other diseases lie in the cell's nucleus. But getting way down to that level -- to see and investigate the important genetic material housed there -- requires creative thinking and extremely powerful imaging techniques. Vadim Backman and Hao Zhang, nanoscale imaging more
Real-Time PCR Quantification of Plant miRNAs Using Universal ProbeLibrary Technology
MicroRNAs (miRNAs) are naturally occurring, highly conserved families of transcripts (18-25 nt in length) that are processed from larger hairpin precursors. Both plant and animal genomes encode miRNAs, and to date, there are over 4000 mature miRNA tr more