Topic biomarkers

News biomarkers

• Inflammatory biomarkers improve the clinical prediction of mortality in COPD

  The addition of changes in inflammatory biomarkers to established clinical variables improves the prediction of mortality in patients with chronic obstructive pulmonary disease (COPD), according to a new study."COPD is characterized by low-grade inflammation, so we hypothesized that the addition of more

• Origenis receives grant to develop new diagnostic tools for the treatment of neurodegenerative disorders

  Origenis has started the development of biomarkers to complement the preclinical in-house development of its therapeutic small molecule inhibitors acting on LRRK2. LRRK2 inhibitors are expected to be useful for the treatment of Parkinson’s disease and other neurodegenerative disorders. The objective more

• UofL receives Bill and Melinda Gates Foundation Grand Challenges TB biomarkers grant

  The University of Louisville announced that it will receive a tuberculosis (TB) biomarkers grant through the Bill & Melinda Gates Foundation's Grand Challenges in Global Health program, an initiative which seeks to overcome persistent bottlenecks in creating new tools that can radically improve heal more

White papers biomarkers

• High sensitive detection of follistatin by Imperacer®: an initial study on the way to analytical gene-doping tests
  

  For the understanding of interactions in the muscle-growth directing myostatin-pathway and therefore also for the establishment of high sensitive detection strategies for gene-doping, detailed studies of protein concentration levels in biological matrices and appropriate highly sensitive analytic techniques for quantitative monitoring of these biomarkers are required. In this work, the development of a high sensitive assay for follistatin based on the Imperacer® technology is described. The quantification limit in human serum was found at 60 pg/ml in only 6 µl sample volume. With this initial assay we demonstrate the first application in a set of analytical tests for a high sensitive myostatin pathway related profiling. more

Websites biomarkers