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  • A look behind Dalí’s paintings

    A collaboration of scientists, conservators and curators has developed a technique for assessing the condition of works of art without the need to remove samples from them, and used it to analyse a valuable collection of paintings by the enigmatic artist Salvador Dalí. Paintings undergo little mecha more

  • Pfeiffer Vacuum: Q3 the best quarter in the company’s history

    Pfeiffer Vacuum closed the month of September with the best quarter ever in its corporate history. This also produced above-average developments for the first nine months. All metrics posted significant, double-digit growth rates. Pfeiffer Vacuum Chief Executive Officer Manfred Bender had this to s more

  • Sniffing out shoe bombs: A new and simple sensor for explosive chemicals

    University of Illinois chemists have developed a simple sensor to detect an explosive used in shoe bombs. It could lead to inexpensive, easy-to-use devices for luggage and passenger screening at airports and elsewhere. Triacetone triperoxide (TATP) is a high-powered explosive that in recent years h more

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  • LightCycler® 480 System: High-throughput Gene Expression and Genotyping Analysis - A Performance Study

    The LightCycler® 480 System is a novel platform for rapid gene expression and melting curve-based genotyping for medium- and high-throughput. In order to assess the performance and ease-of-use of the complete LightCycler® 480 System (instrument, software, and reagents) in an academic laboratory setting we scheduled a high-throughput project including gene expression (39 targets in 88 samples = 3,400 expression values) as well as genotyping applications (3,808 genotypes; 14 SNPs in 288 samples). The project, involving five technicians and two graduate students, was accomplished within 15 working days. more

  • Genotypes in Smokers: Correlations with Smoking Behavior

    Smoking behavior is influenced by both genetic and environmental factors. Moreover, smoking initiation and smoking persistence have a heritability of at least 50%. A large body of work has been dedicated to associating multiple genetic markers of neurobiological pathways previously linked to addiction and smoking such as the central dopaminergic, serotoninergic, and nicotinergic pathways with different aspects of smoking behavior. In order to investigate the feasability of future genetic analyses, we genotyped 14 SNPs in 288 samples of addicted smokers using the LightCycler® 480 System with HybProbe assays. more

  • Pressure Digestion for Sample Preparation

    What analyst does not wish for a universal method for processing all his or her samples? Pressure digestion represents just such a procedure for sample digestions and is therefore one of the standard sample preparation procedures currently employed in analytical chemistry for element quantification more

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