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  • A look behind Dalí’s paintings

    A collaboration of scientists, conservators and curators has developed a technique for assessing the condition of works of art without the need to remove samples from them, and used it to analyse a valuable collection of paintings by the enigmatic artist Salvador Dalí. Paintings undergo little mecha more

  • Pfeiffer Vacuum: Q3 the best quarter in the company’s history

    Pfeiffer Vacuum closed the month of September with the best quarter ever in its corporate history. This also produced above-average developments for the first nine months. All metrics posted significant, double-digit growth rates. Pfeiffer Vacuum Chief Executive Officer Manfred Bender had this to s more

  • Sniffing out shoe bombs: A new and simple sensor for explosive chemicals

    University of Illinois chemists have developed a simple sensor to detect an explosive used in shoe bombs. It could lead to inexpensive, easy-to-use devices for luggage and passenger screening at airports and elsewhere. Triacetone triperoxide (TATP) is a high-powered explosive that in recent years h more

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  • Do you see the complete picture?

    Gel permeation chromatography (GPC) or also named size exclusion chromatography (SEC) is the most often used method for determining the molecular weight of natural and synthetic macromolecules. One specific strength of this method lies in the fact that by the separation process the whole molecular weight distribution is obtained. The molecular weight distribution contains much larger information for the characterization of polymer samples compared to a single value. more

  • Real-Time PCR Quantification of Plant miRNAs Using Universal ProbeLibrary Technology

    MicroRNAs (miRNAs) are naturally occurring, highly conserved families of transcripts (18-25 nt in length) that are processed from larger hairpin precursors. Both plant and animal genomes encode miRNAs, and to date, there are over 4000 mature miRNA transcripts annotated. Although miRNAs represent a relatively abundant class of transcripts, their expression levels vary greatly among species and tissues. Less abundant miRNAs routinely fail detection using technologies such as cloning, northern hybridization and microarray analysis. Here, we present a real-time quantification method for accurate, sensitive, and economical detection of plant miRNAs based upon the stem-loop RT primer approach using an miRNA-specific primer coupled with a stem-loop specific Universal ProbeLibrary (UPL) probe. This approach represents a highly specific, sensitive, and easy-to-apply system to detect miRNAs. more

  • Looxster® - Enrichment and isolation of bacterial DNA using Pureprove® Technology

    Detection of the bacterial content of a specific sample, irrelevant from its source (i.e. Clinical, Food or Environmental), is not as straightforward as it seems. In clinical microbiology laboratories, the gold standard method for the detection of pathogens in patients suspected of systemic infections is the blood culture. However, this technique is known to have many drawbacks especially with regard to non-cultivable organisms, low abundance (longer lag phase) and patient's antibiotics treatment. more

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