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Dynamic Light Scattering - an Important Tool for Protein Crystallography and Nanotechnology
Dynamic Light Scattering (DLS) is an established technique in the field of protein crystallography. DLS is used to measure hydrodynamic sizes, polydispersities and aggregation effects of protein samples. These are important parameters for the crystallisation of proteins. DLS is also used in the nanotechnology research for the accurate and fast size measurement of nanoparticles made of different materials....
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On-line particle analysis in wet processes
Fully automated particle size measurement technology integrated with existing plant control platforms for ease of use has the potential to deliver numerous benefits. At plants where a switch to on-line analysis has been made it is frequently easier or possible to:...
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Measuring particle size using modern laser diffraction techniques
Many different techniques have been devised for determining particle size distribution, but for a wide range of industries laser diffraction has become the preferred choice. Laser diffraction, alternatively referred to as Low Angle Laser Light Scattering (LALLS), can be used for the non-destructive analysis of wet or dry samples, with particles in the size range 0.02 to 2000 micron and has inherent advantages which make it preferable to other options for many different materials....
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Particle shape - an important parameter in pharmaceutical manufacturing
The advent of rapid and reliable measurement technologies, together with the FDA's PAT (Process Analytical Technologies) initiative, has increased the use of particle shape analysis within the pharmaceutical industry. Particle shape, like particle size which is routinely measured and controlled, can directly influence product performance and its measurement can lead to improved process and product understanding. Here we consider the importance of particle shape measurement for the pharmaceutical industry, with reference to the aims of the PAT initiative, and highlight the modern image analysis techniques available for sensitive size and shape characterization....
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Making the connection - particle size, size distribution and rheology
A number of factors influence the rheology of a suspension, including particle size, particle size distribution, and the volume fraction of solids present. Here we examine the relationship between rheology and particle size parameters. Commonly used rheological terms are described and we present data from example systems to illustrate key points...
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